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The 2024 film is an award-winning body-horror satire available to stream on MUBI and HBO Max . Directed by Coralie Fargeat, the movie stars Demi Moore as Elisabeth Sparkle, an aging celebrity who uses a black-market drug to create a younger version of herself, played by Margaret Qualley . Film Overview
Upon injection, Elisabeth spawns a youthful counterpart named Sue (played by ). The rules are strict: they must alternate control every seven days, sharing one life in a delicate balance. However, as Sue’s popularity grows and Elisabeth’s self-loathing deepens, the balance is shattered, leading to horrific side effects and a bloody struggle for survival. Production and Critical Reception The Substance Official Trailer (2024) Demi Moore