Yes. HEN 3.0 or higher handles large PKGs fine. Just ensure you enable HEN before installing.
If you have downloaded a "fixed" version of Final Fantasy XIII, follow these steps to ensure a successful boot: final fantasy 13 ps3 pkg fixed
: Many of these fixed PKGs are tested to run on 4.80+ CFW and HEN systems, ensuring they work on both older custom firmware and newer Homebrew ENabler environments. final fantasy 13 ps3 pkg fixed