: These are typically created through "grafting-from" (growing side chains from an active backbone), "grafting-onto" (attaching pre-made chains), or "grafting-through" (polymerizing macromonomers). 2. Polyguanine (Poly-G) Nucleic Acids
❌ – Extended glycine runs can promote pathological fibrils (e.g., in some neurodegeneration models). ❌ Difficult to study – Highly flexible regions often appear as "disordered" in crystallography. ❌ Limited drug targeting – Lack of hydrophobic pockets makes them hard to inhibit. g poly
The future of G Poly looks promising, with ongoing research and development in various fields, including tissue engineering, regenerative medicine, and cosmetic surgery. "grafting-onto" (attaching pre-made chains)
: "Interaction of Poly(L-Lysine)-g-Poly(Ethylene Glycol) with Supported Phospholipid Bilayers" on PubMed Central . including tissue engineering